Shanghai Chemtron Biotech Co.Ltd.

Clinical Significance Of Detecting Streptococcus GBS

GBS, which normally reside in the vagina and rectum, is a conditional pathogenic bacterium. Generally, GBS infection in normal healthy people does not cause disease.

According to statistics, about 10% to 30% of pregnant women are infected with GBS, and 40% to 70% of them will be transmitted to the newborn during childbirth. If the bacteria are present in newborns, about 1 to 3 percent of them will develop early invasive infections, and 5 percent of them will die.
GBS infection induces a variety of maternal diseases
Maternal infection is characterized by bacteremia, urinary tract infection, fetal membrane infection, endometrium infection and trauma infection.

GBS infection is the main factor of premature rupture of membranes
GBS has a strong adsorption capacity and penetration ability to the chorionic membrane, which can be absorbed into the maternal tissue within 2 hours after inoculation, and then invade the chorionic membrane. Through the phagocytosis of inflammatory cells and direct invasion of proteolytic enzymes produced by bacteria, the local tension of the membranes is reduced, leading to premature rupture of the membranes. It has been reported that the incidence of premature rupture of membranes with GBS in the urine of 2,745 women is 35%.

GBS infection is highly susceptible to amniotic cavity infection
It was reported that 21% of GBS positive pregnant women had chorioamnionitis and postpartum endometritis, and analysis indicated that GBS positive was an important risk factor for chorioamnionitis.

The rate of preterm birth induced by GBS infection is up to 60%
Studies have shown that GBS positive pregnant women are 20 to 60 percent more likely to give birth to premature babies with low birth weight and very low birth weight.

GBS is the main pathogen of puerperal infection
Puerperal infection refers to reproductive tract infection  by pathogens during childbirth and puerperal period, causing local and systemic inflammatory response. The incidence of puerperal infection ranged from 1% to 7.2%, one of the four major causes of maternal death. GBS is the main pathogen causing puerperal infection.

Neonatal infection with GBS induces a variety of diseases and even death
The main route of GBS transmission is vertical transmission and is related to childbirth. If a pregnant woman is infected with GBS, the newborn may inhale infected amniotic fluid at birth or infect GBS through the birth canal. Uterine labor does not prevent the newborn from contracting GBS.
According to the time of infection, neonatal infection can be divided into early invasive infection (within 7 days of birth) and late invasive infection (after 7 days of birth).


Neonatal infection GBS is mainly manifested as early invasive infection, and early invasive infection is mainly manifested by neonatal sepsis.

Neonatal infection with GBS can lead to sepsis, pneumonia and meningitis, high morbidity and mortality, and may also leave behind long-term pathological conditions such as deafness, impaired vision, developmental disorders and cerebral palsy.

The annual incidence of sepsis among newborns was 2.7 percent, according to the 10-year new haven regional survey. About half of its neonatal sepsis is caused by group B streptococcus infection.

Prenatal screening for GBS is particularly important because of the severity of symptoms and diseases associated with GBS infection in pregnant women and newborns. Delivery transmission is the main route of neonatal GBS infection. Therefore, antibiotic prevention can effectively reduce the vertical transmission of GBS and lead to early neonatal invasive infection.

Chemtron biotech otc rapid strep test is of high quality. Learn more about the otc rapid strep test from chemtron biotech.

Related News
  • Characteristics of HCV Detection Kit

    Characteristics of HCV Detection Kit

    July 26, 2018It shortens the "window period" of HCV infection, which is 70 days to 2 years shorter than the "window period" of HCV antibody detection currently used in the marketThe vaccine can be used to diagnose...view
  • The Best Time for Ovarian Function Examination

    The Best Time for Ovarian Function Examination

    July 26, 20181. Gynecological ultrasonography: around the third day of menstruationUnder the b-mode ultrasound, you can see a lot of small follicles in the ovaries. These follicles are the "small houses" of the eg...view
  • Rapid Kit For HCV Nucleic Acid Detection And Its Detection Method 1

    Rapid Kit For HCV Nucleic Acid Detection And Its Detection Method 1

    July 26, 2018Chemtron biotech's present invention discloses a kit for rapid step detection of HCV nucleic acid, including nucleic acid extract, rt-qpcr reaction fluid, negative control, positive control and positi...view
  • What Are the Symptoms of Menopause

    What Are the Symptoms of Menopause

    July 26, 2018Every woman has to deal with menopause. During this period, women have to deal with a lot of problems because of physical, mental and emotional abnormalities. Understanding the signs and symptoms of m...view
  • Precautions For Chlamydia Detection

    Precautions For Chlamydia Detection

    August 8, 20181. Diagnosis outside the donor and use by professionals only.2. Do not use after expiration: do not mix different batches of reagents or test kits for use;3. Do not mix the lid of solution A and solut...view
  • Immunoquantitative Analyzer

    Immunoquantitative Analyzer

    August 8, 2018[Intended use]: it is used in conjunction with the company's immune-chromatography matching agent for the quantitative analysis of the substances to be tested in human serum, plasma or whole blood sam...view
  • TEL:+86-21-68129666
  • FAX:+86-21-68129222
  • EMAIL:international@chemtronbio.com
  • ADDRESS:No.518, Qingdai Rd., International Medical Park, Pudong, 201318, Shanghai, P.R.China