1. Early predictive value of renal damage in hypertension
The urinary albumin of hypertensive patients is significantly higher than that of normal people, which is positively correlated with the increase of blood pressure, the increase of pressure in the glomerulus, and the imbalance of albumin filtration function. It can help to understand the extent of early kidney damage. One of the earliest signs of renal lesions is the increase of urinary microalbumin, which can also be regarded as an important risk factor and sensitive indicator of vascular lesions.
2. Application value of diabetes
It can predict the development and early diagnosis of diabetic nephropathy. The earliest clinical signal of diabetic nephropathy is that the urinary albumin excretion rate keeps increasing and microalbuminuria occurs. ALB<30 mg/L is normal albuminuria period. When ALB is in the high value stage of microalbuminuria at 30-299 mg/L, combined with clinical symptoms, it indicates the trend of early diabetic nephropathy. It is generally believed that the lesion can be recovered after treatment and the urinary microalbumin can turn negative.
3. Application in other diseases
Indicators of renal function in systemic or local inflammatory responses, such as early renal lesions caused by urinary tract infection. The predictors of the complications of acute pancreatitis were severe complications in patients with high Alb, and no complications occurred in patients with < 200mg/L. Taking drugs that have an impact on renal function can also detect urinary microalbumin, so as to facilitate early observation of renal function and early adoption of measures. Sensitive indicators for the diagnosis of kidney and urinary system diseases.
4. Status quo and sociological significance of urine microalbumin test detection
The incidence of kidney disease is very high, with Chen nan in Shanghai reporting 11.8%. Japan 13.7 percent, the United States 11 percent. The real cure for nephropathy is that in the early stage of urinary microalbumin, kidney damage is in the reversible stage. Once it enters the irreversible stage, the disease can only be treated.
The relationship between prevention and treatment: early detection of urinary microscopy (ALB) costs little, and the treatment after the formation of uremia, such as dialysis, costs about 100,000 yuan/year, which consumes a lot of medical insurance funds. Therefore, it is very important to pay attention to urine microscopy at an early stage. The world health organization attaches great importance to the prevention and treatment of nephropathy, which is designated as world kidney disease day on the second Thursday of march every year. Shanghai has made a lot of publicity for the prevention and treatment of kidney disease and the early detection of urine microscopy.
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