Shanghai Chemtron Biotech Co.Ltd.

The Importance of Cardiac Troponin I

CTnI will be elevated in the blood of patients with myocarditis. Smith et al. studied 53 patients with myocarditis and found that the plasma cTnI level of 18 patients is significantly increased, while only 3 patients had increased ck-mb level. Therefore, cTnI is more sensitive to myocardial injury than ck-mb, and can be a specific and sensitive indicator of serum in myocarditis.

Stromal cardiac troponin I is also important in the clinical treatment and prognosis of heart disease
Vecchia et al. continuously measured the plasma cTnI levels of 26 hospitalized or outpatient patients with mental failure by immunofluorescence, and found that 6 patients had significantly increased cTnI levels, among which 3 died, 3 patients became normal after treatment, and 20 patients with normal plasma cTnI maintained normal new functions. The measurement of cTnI in serum of unstable angina patients is helpful to predict the occurrence of myocardial infarction. For patients with acute coronary syndromes, plasma cTnI levels can provide prognostic information and early identification of patients at risk of death. Serum cTnI can be used to determine the degree of myocardial injury and prognosis in patients with supraventricular tachycardia treated by electrocardiography.

The clinical diagnosis of myocardial infarction and mild coronary ischemia syndrome is difficult, especially in emergencies, when the patient's symptoms are not typical or the electrocardiogram diagnosis is not clear. Biochemical detection of myocardial specific cTnI provides a new diagnostic basis. Application of cTnI determination can be detected clinically asymptomatic myocardial ischemia patients, improve the diagnostic positive rate of myocardial ischemia, such as the marathon athletes, skeletal muscle damage, muscle pathological changes etc. So some people think that the plasma cTnI on myocardial damage 100% sensitive and specific which is a golden diagnosis of myocardial injury index. The reasons are the following:

A. The only type of cTnI is found in cardiac tissue.
B. Circulating cTnI is not expressed in skeletal muscle injury;
C. When measuring cTnI and skeletal muscle TnI with antibodies, there is no crossover reaction.
D. Ck-mb in patients with long-term endurance exercise or kidney diseaseis increased, but cTnI is not increased.
E. Correspondingly increased cTnI is closely related to myocardial injury prediction.
F. The cTnI concentration in the hollow heart is 13 times higher than that of ck-mb, so cTnI is more sensitive than ck-mb.
G. Tool is not affected by hypothyroidism.

Therefore, the detection of cTnI is sensitive and specific to heart diseases, and has a wide application prospect in the diagnosis of cardiovascular diseases.

Chemtron biotech
troponin i rapid test kit is of high quality. Learn more about the troponin i rapid test kit from chemtron biotech.
Related News
  • How To Test Pregnancy

    How To Test Pregnancy

    August 8, 2018Self-test method: to detect pregnancy according to the changes in the bodyFor example, observe your menstrual period. If your menstruation period is relatively regular, it is possible that you are pre...view
  • Cardiac Troponin I Test Paper

    Cardiac Troponin I Test Paper

    August 8, 2018Myocardial calcium protein I test paper is a cardiac protein with molecular weight of 22.5KD, which forms a cardiac calcium protein complex together with troponin T(TnT) and troponin C (TnC) to jointl...view
  • Application Of Chlamydia Test Reagent In Women

    Application Of Chlamydia Test Reagent In Women

    August 8, 2018Intended use:It is suitable for screening suspected chlamydia trachomatis infection by various medical institutions, and can qualitatively detect whether chlamydia trachomatis antigen is contained in ...view
  • What's The Food For Menopause

    What's The Food For Menopause

    July 26, 2018Menopause is a necessary stage for every woman. During this long and special period of time, women will have a lot of physical abnormalities. So when women reach menopause, what food can they eat to r...view
  • What Are the Symptoms of Menopause

    What Are the Symptoms of Menopause

    July 26, 2018Every woman has to deal with menopause. During this period, women have to deal with a lot of problems because of physical, mental and emotional abnormalities. Understanding the signs and symptoms of m...view
  • Detection Of Hepatitis B Virus DNA

    Detection Of Hepatitis B Virus DNA

    August 8, 2018HBV DNA detection is a technique to detect HBV by DNA, which is a common method to determine HBV replication. In general, a number greater than 10 to the third power is positive, a number greater than...view
  • TEL:+86-21-68129666
  • FAX:+86-21-68129222
  • EMAIL:international@chemtronbio.com
  • ADDRESS:No.518, Qingdai Rd., International Medical Park, Pudong, 201318, Shanghai, P.R.China