Shanghai Chemtron Biotech Co.Ltd.

MAU Test and Method 3

Microalbuminuria refers to the presence of microalbuminuria in the urine. Albumin is a normal protein in the blood, but only a small amount of albumin appears in the urine under physiological conditions. Microalbuminuria reflects abnormal protein leakage in the kidney. The increase of urinary microalbumin is an early sensitive index of renal injury, which is commonly seen in diabetic nephropathy, hypertension and preeclampsia. Urinary microalbumin caused by any disease is the damage of renal intrinsic cells caused by different initial causes, which changes the structure of renal intrinsic cells, and changes the function with the structure, which is reflected in urine. Microalbuminuria is also a sign of changes in the whole vascular system, and can be considered as a "window" of arterial disease, because it is an early indication of changes in the kidney and cardiovascular system.
Urinary microalbumin can be determined by immunoturbidimetry, immunofluorescence, radioimmunoassay, enzyme immunoassay and other methods. Radioimmunoassay has high sensitivity and specificity, but it has some shortcomings such as radioactive contamination and short storage time of reagents. At present, ELISA is still the most widely used method for the detection of urinary microalbumin in China, but the enzyme labeling method has many steps, so its repeatability is poor. The carboxylated polystyrene latex sensitized by albumin and the immunolatex agglutination inhibition test were established for the determination of urinary microalbumin. It has the advantages of rapidity, specificity, simplicity and low cost.
Shanghai Kaichuang Biology provides a MAU test based on latex enhanced immunoturbidimetry, the MAU test is a liquid double reagent, including reagents R1 and R2. The reagent R1 is a reactant and the reagent R2 is a solution containing albumin immunolatex particles. It is characterized by chemical crosslinking and covalent crosslinking of antibodies with carboxylated polystyrene latex by water-soluble carbodiimide (EDC) and N-hydroxy succinimide (NHS) to form mAlb antibody latex reagent. This reagent has high sensitivity, strong specificity and simple preparation. It is worth further popularizing and using.
Related News
  • Characteristics of HCV Detection Kit

    Characteristics of HCV Detection Kit

    July 26, 2018It shortens the "window period" of HCV infection, which is 70 days to 2 years shorter than the "window period" of HCV antibody detection currently used in the marketThe vaccine can be used to diagnose...view
  • FOB Colorectal Cancer Screening

    FOB Colorectal Cancer Screening

    July 26, 2018Colorectal cancer can evolve without any early warning of inflammation, and cancer can spread to other parts of the body after years of growth in the inner wall of the large intestine. Before the onse...view
  • Application Of Chlamydia Test Reagent In Women

    Application Of Chlamydia Test Reagent In Women

    August 8, 2018Intended use:It is suitable for screening suspected chlamydia trachomatis infection by various medical institutions, and can qualitatively detect whether chlamydia trachomatis antigen is contained in ...view
  • Announcements of One Step 10miu Pregnancy Test

    Announcements of One Step 10miu Pregnancy Test

    August 8, 20181. Pay attention to the production date on the packaging box, and do not use expired test CARDS, because chemical agents will be ineffective if they take too long.2. In order to reduce the probability...view
  • Clinical significance of FSH

    Clinical significance of FSH

    April 9, 2019Why test for ovarian function? Ovary is the organ that produces sex hormone (estrogen), estrogen releases to the organ that needs estrogen to a lot of to need after blood circulates: mammary gland, ut...view
  • Immunoquantitative Analyzer

    Immunoquantitative Analyzer

    August 8, 2018[Intended use]: it is used in conjunction with the company's immune-chromatography matching agent for the quantitative analysis of the substances to be tested in human serum, plasma or whole blood sam...view
  • TEL:+86-21-68129666
  • FAX:+86-21-68129222
  • ADDRESS:No.518, Qingdai Rd., International Medical Park, Pudong, 201318, Shanghai, P.R.China